Endocrine Abstracts

Aim: To study the effect of testosterone replacement treatment in the aging male with T2DM.Material and methods: Twenty-six hypogonadal men with T2DM and late-onset hypogonadism (Total testosterone at diagnosis <12 nmol/l) between the age 50–65 years (55.00 (50.00;58.00)) were treated with a 1% testosterone gel (AndroGel) (5 g/day) within 6 months. Patients were assessed before the first using of AndroGel, in one week interval and in 6 months. A...

Aim: To clarify the contribution of leptin to bone mineral density (BMD) in men with type 2 diabetes mellitus (DT2).Materials: We screened 168 Belorussian men aged 50–65 years. Plasma TC, HDL-C, LDL-C, VLDL-C, TG concentrations, HbA1c, IRI, CRP, total testosterone were assessed. BMD was evaluated using dual-energy X-ray absorptiometry (DXA). BMD was expressed as a T score. All statistical analyses were performed using SPSS v11.0 software....

Aims: Anemia occurs early and predicts high risk of cardiovascular events and death in patients with diabetic nephropathy. The aim of this study was to assess the influence of anemia on the quality of life of patients with early diabetic nephropathy.Methods: We investigated 95 anemic and 32 non-anemic patients with type 2 diabetes mellitus and early diabetic nephropathy (CKD stages 1–3). Anemia was defined according to WHO criteria. Anemic patients ...

The aim: To investigate the prevalence of subclinical late-onset hypogonadism (SLOH) in men with diabetes type 2 and relationship between testosterone concentrations and duration of diabetes.Material and methods: We investigated 114 men with DT 2 aged from 45–60 years (M±SD 54.0±4.63). Luteinizing hormone (LH), follicle-stimulating hormone (FSH), total testosterone (T), calculated free testosterone (cFT) and bioavailable testosterone (bT),...